Sunday, February 17, 2013

Video: Roundtable reviews McCain?s remarks

A Second Take on Meeting the Press: From an up-close look at Rachel Maddow's sneakers to an in-depth look at Jon Krakauer's latest book ? it's all fair game in our "Meet the Press: Take Two" web extra. Log on Sundays to see David Gregory's post-show conversations with leading newsmakers, authors and roundtable guests. Videos are available on-demand by 12 p.m. ET on Sundays.

Source: http://www.nbcnews.com/id/3032608/vp/50839847#50839847

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Hundreds hurt as meteorite hits Russia

CHELYABINSK, Russia (Reuters) - More than 500 people were injured when a meteorite shot across the sky and exploded over central Russia on Friday, sending fireballs crashing to Earth, shattering windows and damaging buildings.

People heading to work in Chelyabinsk heard what sounded like an explosion, saw a bright light and then felt a shockwave according to a Reuters correspondent in the industrial city 1,500 km (950 miles) east of Moscow.

A fireball blazed across the horizon, leaving a long white trail in its wake which could be seen as far as 200 km (125 miles) away in Yekaterinburg. Car alarms went off, windows shattered and mobile phone networks were interrupted.

"I was driving to work, it was quite dark, but it suddenly became as bright as if it was day," said Viktor Prokofiev, 36, a resident of Yekaterinburg in the Urals Mountains.

"I felt like I was blinded by headlights," he said.

No fatalities were reported but President Vladimir Putin, who was due to host Finance Ministry officials from the Group of 20 nations in Moscow, and Prime Minister Dmitry Medvedev were informed.

A local ministry official said such incidents were extremely rare and Friday's events might have been linked to an asteroid the size of an Olympic swimming pool due to pass Earth at a distance of 27,520 km (17,100 miles) but this was not confirmed.

Russia's space agency Roscosmos said the meteorite was travelling at a speed of 30 km (19 miles) per second and that such events were hard to predict. The Interior Ministry said the meteorite explosion had caused a sonic boom.

Russia's Emergencies Ministry said 514 people had sought medical help, mainly for light injuries caused by flying glass, and that 112 of those were kept in hospital. Search groups were set up to look for the remains of the meteorite.

"There have never been any cases of meteorites breaking up at such a low level over Russia before," said Yuri Burenko, head of the Chelyabinsk branch of the Emergencies Ministry.

WINDOWS BREAK, FRAMES BUCKLE

Windows were shattered on Chelyabinsk's central Lenin Street and some of the frames of shop fronts buckled.

A loud noise, resembling an explosion, rang out at around 9.20 a.m. (12:20 a.m. ET). The shockwave could be felt in apartment buildings in the industrial city's center.

"I was standing at a bus stop, seeing off my girlfriend," said Andrei, a local resident who did not give his second name. "Then there was a flash and I saw a trail of smoke across the sky and felt a shockwave that smashed windows."

A wall was damaged at the Chelyabinsk Zinc Plant but a spokeswoman said there was no environmental threat.

Although such events are rare, a meteorite is thought to have devastated an area of more than 2,000 sq km (1,250 miles) in Siberia in 1908, smashing windows as far as 200 km (125 miles) from the point of impact.

The Emergencies Ministry described Friday's events as a "meteor shower in the form of fireballs" and said background radiation levels were normal. It urged residents not to panic.

Chelyabinsk city authorities urged people to stay indoors unless they needed to pick up their children from schools and kindergartens. They said what sounded like a blast had been heard at an altitude of 10,000 meters (32,800 feet).

The U.S. space agency NASA has said an asteroid known as 2012 DA14, about 46 meters in diameter, would have an encounter with Earth closer than any asteroid since scientists began routinely monitoring them about 15 years ago.

Television, weather and communications satellites fly about 500 miles higher. The moon is 14 times farther away.

(Additional reporting by Natalia Shurmina in Yekaterinburg and Gabriela Baczynska in Moscow, Writing by Alexei Anishchuk and Timothy Heritage, Editing by Michael Holden)

Source: http://news.yahoo.com/possible-meteor-shower-reported-eastern-russia-052833588.html

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Meet Your Doppelganger On Sodisco. A First Look At Ex-Payvment ...

Lonely? Wish you had someone to geek out with about the weird stuff you?re into? Sodisco wants to find you a play date. It?s the soon-to-launch startup from Christian Taylor, ex-CEO of Facebook e-commerce platform Payvment, which just got bought by Intuit. Taylor called me up to reveal what Sodisco?s all about: analyzing your interests and introducing you to your nearest clones.

?There are people three blocks away from me who like the same things as me, but there was no platform out there to connect us,? Taylor tells me. Well, there are some others that try to connect you, but Sodisco wants to go all algorithmic on social discovery. Taylor explains, ?I moved to San Francisco by myself. I ride a motorcycle and collect vintage lunch boxes.? He wanted people to share his hobbies with, and he thinks it?s a common problem.

ChristianThe solution came to him while still at Payvment, which raised $7.75 million and served 200,000 merchants before selling. The company was analyzing people?s interests to see what e-commerce products it should recommend to them. Essentially, it would say ?people with similar interests to you bought this.? Taylor realized, ?hey, maybe we should just introduce these folks.?

So after priming Payvment for its acquisition by Intuit, and grabbing some vacation while the deal closed under new CEO Jim Stoneham, he began work on Sodisco. It?s named after comedian Eddie Izzard?s complement to people he thinks are cool: ?You are so disco!? Now the startup is raising a seed round and building out a team. Taylor has already roped in Ping.fm CEO and co-founder of LaunchRock Sean McCullough as CTO.

Sodisco_ios2 ScreenshotTogether they?re building a mobile and web application that ?provides localized discussion communities around the interests you?re passionate about and enables you to discover new people in your geographic area who share those same passions and interests.? Users will be able to join groups around interests, post related content and exchange messages with other members.

Getting us to actually use the app will be the challenge. In a space cluttered with ways to connect with people, it may take a mini-miracle to convince users to frequent another site. Taylor admits ?the world does not need one more friending app.? He doesn?t want his Facebook news feed any more cluttered than it is. Rather than a social network, though, Taylor likens Sodisco to Reddit.

But unlike normal online forums, the goal is to transcend the screen and get people to hang out in meatspace. And different from most offline meetups, Sodisco matches you with people you not only share a specific interest with, but that you?re generally compatible with, too.

Taylor concludes, ?When I bought a motorcycle, I wanted to find people to ride with. I?d go to meet-ups, but just because we both like motorcycles doesn?t mean I?m gonna be friends with some big burly dude or some 20-year-old. It became so apparent to me that this was something I had the tech to solve.?

Sodisco hasn?t launched yet, but you can sign up to get an early invite when it?s ready.

sodisco Face


Currently Christian is overseeing the startup efforts of Sodisco. Previously he founded the Social Commerce platform company, Payvment, which powers a majority of all shopping on the worlds largest social networks as well as Payvment?s own social product discovery destination, Lish.com. Payvment also developed proprietary social ad targeting technology. When he?s not changing how the world discovers great products and people on social networks, Christian can be found speaking somewhere. Occasionally writing for publications such as Mashable on the subject...

? Learn more

Source: http://techcrunch.com/2013/02/15/sodisco/

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Saturday, February 16, 2013

GameStick's $79 Android gaming system is available for pre-order ...

PlayJam plans to ship its first Android-based GameStick video game consoles in April to backers of the company?s Kickstarter campaign. But if you didn?t pledge any money during the fundraising campaign, now you can pre-order a GameStick from the company?s website for $79.

The GameStick is a game console on a tiny stick about the size of a USB flash drive. It also comes with a wireless game controller which has a slot that you can store the stick in when you?re not using it.

GameStick

If the GameStick design looks familiar, that?s because it?s basically a custom version of an Android TV Stick ? and we?ve seen a lot of those in the past year. This particular model features an Amlogic AM8726-MX ARM Cortex-A9 processor, 1GB of RAM, 8GB of storage, WiFi, Bluetooth, and an Android Jelly Bean-based operating system with an emphasis on games.

Pre-orders will ship once all of the Kickstarter premiums are out the door.

Customers can also pick up a case for $10, or a dock for $25. The dock is an accessory that adds an SD card reader, additional USB ports, an Ethernet jack, HDMI port, and wireless charging for the GameStick controller. You can also use it to plug in peripherals like a microphone, camera, or just about anything else supported by Android.

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  • Game formatDownloadable
  • Controller typeWireless
  • Video outputsHDMI
  • Released04/01/2013
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Source: http://liliputing.com/2013/02/gamesticks-79-android-gaming-system-is-available-for-pre-order.html

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Wednesday, February 13, 2013

South Africa Under-19s v England Under-19s

1st Youth ODI: South Africa Under-19s v England Under-19s at Paarl, Feb 13, 2013 | Live Scorecard | ESPN Cricinfo We see you have Google Chrome installed. Try out Cricinfo's free extension: show me no thanks England Under-19s tour of South Africa, 1st Youth ODI: South Africa Under-19s v England Under-19s at Paarl, Feb 13, 2013

Source: http://www.cricinfo.com/ci/engine/match/593031.html?CMP=OTC-RSS

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Tuesday, February 12, 2013

Got to go? Scientists figure out how you know

Monday, February 11, 2013

If you have an overactive bladder or incontinence, help could be on the way. A new research report published online in the FASEB Journal, shows that the epithelium, a thin layer of cells which line the surface of the bladder, is able to sense how full the bladder is through the action of a family of proteins called integrins. As the bladder becomes full, the cells in the epithelium stretch and become thinner, which activates the integrins to send that information to nerves and other cells in the bladder. As a result of this new knowledge, researchers may one day be able to design drugs that target this mechanism to treat conditions like incontinence and overactive bladder, both of which are common, serious, problems affecting millions of people.

"I am very hopeful that as we learn more about how the bladder senses fullness and conveys that information to the nerves and the muscles which control our ability to urinate, that this greater understanding and knowledge will lead to new treatments," said Warren G. Hill, Ph.D., a researcher involved in the work from the Department of Medicine at Beth Israel Deaconess Medical Center and Harvard Medical School in Boston, MA. "It is extremely important that we do this as quickly as possible, since there are millions of people who suffer enormously from the anguish of bladder pain, incontinence and constant feelings of needing to go. I am optimistic these new insights into the role of integrins will begin the process of discovering important new drug targets which will dramatically improve the quality of life for many of these people."

To make this discovery, Hill and colleagues tested two groups of mice. The first were genetically modified to not have an important member of the integrin family present in the epithelium. The second group of mice was normal. The mice lacking the integrin protein had normal looking bladders but very little urinary control. The normal mice also had normal looking bladders, but as expected, had bladder control. Researchers then tested the bladders from the integrin knockout mice and found that their bladders were constantly squeezing and very overactive. In addition, they overfilled their bladders and took much longer to urinate than the normal mice. Since most drug treatments for overactive bladder target proteins in the muscle surrounding the bladder, this study shows that it may be possible to design drugs that target sensory proteins in the epithelium.

"No one wants to pee in his or her pants," said Gerald Weissmann, M.D., Editor-in-Chief of the FASEB Journal, "but the reality is that bladder problems ? incontinence, frequency and pain - affect more people than we realize. This report offers hope that new drugs targeting the bladder's epithelium will succeed when current drugs fail."

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Keizo Kanasaki, Weiqun Yu, Maximilian von Bodungen, John D. Larigakis, Megumi Kanasaki, Francisco Ayala de la Pena, Raghu Kalluri, and Warren G. Hill. Loss of ?1-integrin from urothelium results in overactive bladder and incontinence in mice: a mechanosensory rather than structural phenotype. FASEB J doi:10.1096/fj.12-223404 ; http://www.fasebj.org/content/early/2013/02/08/fj.12-223404.abstract

Federation of American Societies for Experimental Biology: http://www.faseb.org

Thanks to Federation of American Societies for Experimental Biology for this article.

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Source: http://www.labspaces.net/126717/Got_to_go__Scientists_figure_out_how_you_know

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